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ICG maleimide马来酰亚胺,ICG-MAL,吲哚菁绿 英文名：ICG maleimide，ICG-MAL 中文名：吲哚菁绿-马来酰亚胺 外观：绿色粉末 溶解度：二氯甲烷 纯度：95%+ 结构式： ICG maleimide马来酰亚胺,ICG-MAL,吲哚菁绿 ICG is a tricarbocyanine-type dye with NIR-absorbing properties (peak absorption around 800 nm) and emission maximum at 807 nm (10% v/vDMSO/PBS). Little absorption in the visible range accounts for the low autofluorescence, tissue absorbance, and scattering at NIR wavelengths (700-900 nm). The maleimide of the ICG dye offers the opportunity to develop optimal conjugates. Maleimide active group provides an efficient and convenient way to selectively link ICG dye to sulfhydryl groups (free thiol, R-SH) on various substrates (antibodies[1], peptides, proteins, oligonucleotides, small molecule drugs etc.) at neutral (physiological) pH without any activation. Maleimides have very low reactivity with amines, alcohols, and phenols (incl. tyrosine and histidine) and do not react with histidine and methionine thus providing very high labeling selectivity. It has been reported that conjugation to some antibodies may cause decrease in fluorescence intensity of ICG bound to antibody due to the formation of H-dimers4. However, fluorescence is restored after cell binding and internalization, which can be used to design an activatable NIR fluorescent probe. Fluorescence intensity of the unbound ICG-antibody conjugate can be dramatically increased (up to 50-fold) by addition of SDS and β-mercaptoethanol, which diminishes π- π stacking5. 相关产品： TCO-PEG-ICG   吲哚菁绿-聚乙二醇-反式环辛炔 ICG-PEG4-Thiol ICG-PEG4-NHS ICG-PEG5-NH2 ICG-PEG4-MAL ICG-PL-PEG  磷脂化的聚乙二醇 ICG-PL-PEG-FA ICG-PEG-Folate 吲哚菁绿-聚乙二醇-叶酸 ICG-FA-PPD  吲哚菁绿-叶酸修饰PEI-PEG-钆酸 RGD-PLS-ICG  吲哚菁绿-RGD修饰聚乙二醇化脂质体 C18-PEG-ICG ICG-PEG-Silane 吲哚菁绿-聚乙二醇-硅烷 ICG-PEG-Lipoic acid,  ICG-PEG-LA吲哚菁绿-聚乙二醇-硫辛酸 ICG-PEG-Epoxides (EPOX) 吲哚菁绿-聚乙二醇-环氧化物 ICG-PEG-Valeric Acids (VA) 吲哚菁绿-聚乙二醇-缬草酸 ICG-PEG-Chloride 吲哚菁绿修饰聚乙二醇氯化物 ICG-PEG-TZ/Tetrazine  吲哚菁绿修饰聚乙二醇四嗪 ICG-PEG-CHEMS 吲哚菁绿修饰聚乙二醇半琥珀酸胆固醇 ICG-PEG-DBCO  吲哚菁绿修饰聚乙二醇环辛炔 CG-PEG-ICG  吲哚菁绿-聚乙二醇-壳聚糖 ICG-PEG-Chitosan   吲哚菁绿-聚乙二醇-壳聚糖 ICG-PEG-Dextran   吲哚菁绿修饰聚乙二醇葡聚糖/右旋糖酐 ICG-PEG-Galactose  吲哚菁绿修饰聚乙二醇半乳糖 ICG-PEG-Mannose   甘露糖 ICG-PL-PEG-mAb 整合素α(v)β₃单克隆抗体 APT-PEG-ICG-Der-02   MUC1适体的靶配体APT-聚乙二醇-吲哚菁绿 ICG-PEG-MTX  甲氨蝶呤 ICG-PEG-DOX  阿霉素 GNR-PEG-ICG  纳米金棒-聚乙二醇-吲哚菁绿 GNR-PEG-ICG-FA纳米金棒-聚乙二醇-吲哚菁绿-叶酸 Cu9S5@mSiO2-ICG-PEG-LA 核壳结构介孔二氧化硅纳米粒子-吲哚菁绿-聚乙二醇-硫辛酸 PEG-PCL-C3-ICG-NPs    PEG-PCL加有机化合物C3-ICG的纳米粒 双功能ICG衍生物ICG-PEG8-Sulfo-OSu 双功能ICG衍生物ICG-PEG4-Sulfo-OSu ICG衍生物ICG-Sulfo-OSu ICG-PL-PEG 磷脂化的聚乙二醇 ICG-PL-PEG-FA叶酸 磷脂化的聚乙二醇 ICG-FA-PPD 吲哚菁绿-叶酸修饰PEI-PEG-钆酸 RGD-PLS-ICG 吲哚菁绿-RGD修饰聚乙二醇化脂质体 ICG-PEG-Lipoic acid, ICG-PEG-LA吲哚菁绿-聚乙二醇-硫辛酸 ICG-PEG-TZ/Tetrazine 吲哚菁绿修饰聚乙二醇四嗪 ICG-PEG-DBCO 吲哚菁绿修饰聚乙二醇环辛炔 CG-PEG-ICG 吲哚菁绿-聚乙二醇-壳聚糖