MPEG-Silane ,甲氧基PEG硅烷
作者:MPEG-Silane ,甲氧基PEG硅烷 发布时间:2022-08-01 11:15:17
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结构式:
基本信息:
中文名称:甲氧基聚乙二醇硅烷(MPEG-Silane)
中文别名:甲氧基-PEG-硅烷
英文名称:MPEG-Silane
CAS:-
分子量:350、500、550、750、1K、2K、5K、10K、20K
纯度:95%以上
应用简介:
Ethoxyor methoxyl silane functionalized polyethylene glycol, silane PEG (PEG-Si) is a surface reactive PEG derivative that can be used to modify glass, silica and other surfaces via the reaction between hydroxyl group and ethoxyl/methoxylsilane. Pegylation can greatly suppress the non-specific binding of charged moleculesto the modified surfaces. And they have wide applications for medica device,biomems or biocompatible material development.
ReactionProcedures:
Generally,silane PEG is first dissolved in a mixture of ethanol/water solution, thenallow the solution to contact with oxidized glass or silica surface for 30 minto 2 hours. Under this condition, silane PEG should bind to the materialcovalently.
MaterialsRequired:
Pegylationsolution: Ethanol/water (w/w, 95%/5%);
SilanePEG stock solution, 10~50 mg/mL in pegylation solution, prepare in fresh.
Washingsolution: Distilled water.
ReactionSteps:
1.Dissolve targeted materials in Pegylation buffer.
2. Addsilane PEG stock solution to the targeted conjugation materials with the finalconcentration keep at least 10 mg/mL. 10~50 molar excess of silane PEG neededfor optimal conjugation;
3.Allow mixture agitates at room temperature for 30 min at room temperature or 2hours at 4 -20℃.
4. Washout unreacted materials either by distilled water.
物理性质:
状态:液体或者固体,取决于分子量。
溶解性:溶于DMSO,DMF,DCM。
保持条件:-20℃长期保存,避光,干燥。
注意事项:取用一定要干燥,避免频繁的溶解和冻干。
技术指标:
纯度(PEG):95%以上
取代率(SIL):90%以上
分散系数(PDI):小于等于1.05
分析:COA、GPC、NMR、MALDI-TOF
中文名称
货号
英文名、缩写
分子量
规格
价格
甲氧基-PEG-硅烷
PS1-L-5K
MPEG-Silane
5000
1g、5g
现询
甲氧基-PEG-硅烷
PS1-L-2K
MPEG-Silane
2000
1g、5g
现询
甲氧基-PEG-硅烷
PS1-L-1K
MPEG-Silane
1000
1g、5g
现询
甲氧基-PEG-硅烷
PS1-L-10K
MPEG-Silane
10000
1g、5g
现询
甲氧基-PEG-硅烷
PS1-L-20K
MPEG-Silane
20000
1g、5g
现询
(接受特殊分子量的定制:350、550、500、750)