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名称 货号 英文名、缩写 分子量 规格 价格 DBCO-PEG-COOH PS2-CMDB-5K DBCO-PEG-COOH 5000 0.1g、0.5g 现询 DBCO-PEG-COOH PS2-CMDB-2K DBCO-PEG-COOH 2000 0.1g、0.5g 现询 DBCO-PEG-COOH PS2-CMDB-3K DBCO-PEG-COOH 3400 0.1g、0.5g 现询 DBCO-PEG-COOH PS2-CMDB-1K DBCO-PEG-COOH 1000 0.1g、0.5g 现询 DBCO-PEG-COOH PS2-CMDB-10K DBCO-PEG-COOH 10000 0.1g、0.5g 现询 （备注：非常规分子量：400、600。精确聚合度的小分子定制。） 结构式： 基本信息： 中文名称：Dibenzocyclooctyne-聚乙二醇-羧基 (DBCO-PEG-COOH) 别名：DBCO-PEG-COOH 英文名称：DBCO-PEG-COOH，DBCO-PEG-ACID CAS：- 分子量：400、600、1K、2K、3.4K、4K、5K、10K 纯度：95%以上 应用简介： ’DBCO(dibenzocyclooctyne) PEG acid, DBCO-PEG-COOH, is a heterobifunctional reactivePEG derivative that can go Click Chemistry reaction without a need of any metalcatalysts. The strain-promoted 1,3-dipolar cycloaddition of cyclooctynes andazides, also termed as the Cu-free click reaction, is a bioorthogonal reactionthat enables the conjugation of two molecules in aqueous solution. DBCO PEG derivativespossess fast kinetics and stability in aqueous buffer. DBCO reagents can beused to label azide-modified biomolecules spontaneously without the need fortoxic Cu catalysts. Carboxylic acid group, on the other hand, can be activatedto react with amines, hydroxy and other functional groups. Copper-freeClick reaction procedures: Preparethe azide-containing reagents in reaction buffer. AddDBCO reagents to azide containing reagents. Add 1 mol equivalent of limitingreagent to 1.5~3.0 mol equivalents of abundance reagent. Incubatethe reaction at room temperature for 2~4 hours or 2~12 hours at 4 0C. Purifyconjugates either by dialysis or size-exclusion chromatograph. 物理性质： 状态：淡黄色到白色固体，或者半固体，取决于分子量。 溶解性：溶于水，氯仿，DMSO等溶剂。 保持条件：-20℃长期保存，避光，干燥。 注意事项：取用一定要干燥，避免频繁的溶解和冻干。 反应性：DBCO于含有N3基团的反应。NHS可以和NH2。 技术指标： 纯度（PEG）：95%以上 取代率（DBCO）：90%以上 取代率（COOH）：95%以上 分散系数（PDI）：小于等于1.05 分析：COA、GPC、NMR、MALDI-TOF