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DBCO-PEG-MAL,二苯基环辛炔PEG马来酰亚胺,(Dibenzocyclooctyne)PEG
结构式：
基本信息：
中文名：二苯基环辛炔PEG马来酰亚胺，二苯基环辛炔聚乙二醇马来酰亚胺
英文名：DBCO-PEG-MAL, Dibenzocyclooctyne-PEG-Maleimide
分子量：400、600、1K、2K、3.4K、4K、5K、10K
应用简介：
Maleimide PEG DBCO (dibenzocycolctyne) is DBCO PEG derivatives that can go Click Chemistry reaction without a need of any metal catalysts. The strain-promoted 1,3-dipolar cycloaddition of cyclooctynes and azides, also termed as the Cu-free click reaction, is a bioorthogonal reaction that enables the conjugation of two molecules in aueous solution. DBCO PEG derivatives possess fast kinetics and stability in aueous buffer. DBCO reagents can be used to label azide-modified biomolecules spontaneous without the need for toxic Cu catalysts. Meanwhile, maleimide group can react with sulfhydryl (Thoil) groups at pH 6.5-7.5 easily. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.
Copper-free Click Reaction Procedures:
Prepare the azide-containing reagents in reaction buffer.
Add DBCO reagents to azide containing reagents. Add 1 mol euivalent of limiting reagent to 1.5~3.0 mol euivalents of abundance reagent.
Incubate the reaction at room temperature for 2~4 hours or 2~12 hours at 4℃.
Purify conjugates either by dialysis or size-exclusion chromatograph.
物理性质：
状态：淡黄色到黄色固体，或者半固体，取决于分子量。
溶解性：溶于DMSO,DMF等溶剂。
保持条件：-20℃长期保存，避光，干燥。
注意事项：取用一定要干燥，避免频繁的溶解和冻干。
反应性：DBCO于含有N3基团的反应。MAL可以和SH。
DBCO（Dibenzocyclooctyne）PEGs其他产品:
DBCO-PEG-MAL,MW:2000  二苯基环辛炔PEG马来酰亚胺
DBCO-PEG-MAL,MW:3400  二苯基环辛炔PEG马来酰亚胺
DBCO-PEG-MAL,MW:5000  二苯基环辛炔PEG马来酰亚胺
DBCO-PEG-MAL,MW:10000 二苯基环辛炔PEG马来酰亚胺
DBCO-PEG-NH2,MW:2000  二苯基环辛炔PEG氨基
DBCO-PEG-NH2,MW:3400  二苯基环辛炔PEG氨基
DBCO-PEG-NH2,MW:5000  二苯基环辛炔PEG氨基
DBCO-PEG-NH2,MW:10000 二苯基环辛炔PEG氨基
mPEG-DBCO,MW:1000   甲氧基PEG二苯基环辛炔
mPEG-DBCO,MW:2000   甲氧基PEG二苯基环辛炔
mPEG-DBCO,MW:3400   甲氧基PEG二苯基环辛炔
mPEG-DBCO,MW:5000   甲氧基PEG二苯基环辛炔
mPEG-DBCO,MW:10000  甲氧基PEG二苯基环辛炔
mPEG-DBCO,MW:20000  甲氧基PEG二苯基环辛炔    
DBCO-PEG-NHS,MW:2000 二苯基环辛炔PEG活性酯
DBCO-PEG-NHS,MW:3400 二苯基环辛炔PEG活性酯
DBCO-PEG-NHS,MW:5000 二苯基环辛炔PEG活性酯
DBCO-PEG-NHS,MW:10000二苯基环辛炔PEG活性酯
DBCO-PEG-Biotin,MW:2000  二苯基环辛炔PEG生物素
DBCO-PEG-Biotin,MW:3400  二苯基环辛炔PEG生物素
DBCO-PEG-Biotin,MW:5000  二苯基环辛炔PEG生物素
DBCO-PEG-Biotin,MW:10000 二苯基环辛炔PEG生物素
DBCO-PEG-COOH,MW:2000 二苯基环辛炔PEG羧酸
DBCO-PEG-COOH,MW:3400 二苯基环辛炔PEG羧酸
DBCO-PEG-COOH,MW:5000 二苯基环辛炔PEG羧酸
DBCO-PEG-COOH,MW:10000二苯基环辛炔PEG羧酸
DBCO-PEG-Folate,MW:2000  二苯基环辛炔PEG叶酸
DBCO-PEG-Folate,MW:3400  二苯基环辛炔PEG叶酸
DBCO-PEG-Folate,MW:5000  二苯基环辛炔PEG叶酸
DBCO-PEG-Cholesterol,MW:2000 二苯基环辛炔PEG胆固醇
DBCO-PEG-Cholesterol,MW:3400 二苯基环辛炔PEG胆固醇
DBCO-PEG-Cholesterol,MW:5000 二苯基环辛炔PEG胆固醇
DBCO-PEG-Glucose,MW:2000  二苯基环辛炔PEG葡萄糖
DBCO-PEG-Glucose,MW:5000二苯基环辛炔PEG葡萄糖
DBCO-PEG-Silane,MW:2000 二苯基环辛炔PEG硅烷
DBCO-PEG-Silane,MW:3400 二苯基环辛炔PEG硅烷
DBCO-PEG-Silane,MW:5000 二苯基环辛炔PEG硅烷
DBCO-PEG-MAL,二苯基环辛炔PEG马来酰亚胺,(Dibenzocyclooctyne)PEG
Structure M.W. Purity
DBCO-acid & DBCO-PEG acid
DBCO-acid 98%
DBCO-C6-acid 96%
DBCO-PEG4-acid 98%
DBCO-PEG5-acid 95%
DBCO-PEG13-acid 98%
DBCO-CONH-PEG4-acid 95%
DBCO-NHS ester
DBCO-NHS 97%
DBCO-C6-NHS ester 95%
DBCO-Sulfo-NHS ester 97%
DBCO-PEG-NHS ester
DBCO-PEG4-NHS ester 96%
DBCO-PEG5-NHS ester 95%
DBCO-PEG13-NHS ester 90%
DBCO-CONH-PEG4-NHS ester 97%
PC DBCO-PEG4-NHS ester 95%
DBCO-PEG-PFP ester
DBCO-PEG4-PFP ester 95%
DBCO-PEG-Alcohol
DBCO-PEG4-alcohol 95%
DBCO-amine & DBCO-PEG-amine
DBCO-amine 96%
Sulfo DBCO-amine 95%
DBCO-PEG4-amine 98%
Sulfo DBCO-PEG4-amine 95%
DBCO-PEG-NH-Boc
DBCO-PEG4-NH-Boc 97%
BDP FL DBCO
BDP FL DBCO 95%
Fluorescein-DBCO
Fluorescein-DBCO 95%
Carboxyrhodamine-PEG-DBCO
Carboxyrhodamine 110PEG4-DBCO 95%
Sulforhodamine-PEG-DBCO
Sulforhodamine-PEG4-DBCO 95%
TAMRA-PEG-DBCO
TAMRA-PEG4-DBCO 95%
DBCO-Biotin & DBCO-PEG-Biotin
DBCO-PEG4-biotin 95%
DBCO-Sulfo-Link-biotin 95%
DBCO-PEG4-Desthiobiotin 95%
DBCO-PEG-DBCO
DBCO-PEG4-DBCO 95%
DBCO-PEG5-DBCO 95%
DBCO-Maleimide & DBCO-PEG-Maleimide
DBCO-Maleimide 95%
Sulfo DBCO-Maleimide 95%
DBCO-PEG4-Maleimide 95%
Sulfo DBCO-PEG4-Maleimide 90%
TCO-PEG-DBCO
TCO-PEG12-DBCO 95%
Tetrazine-PEG-DBCO
Methyltetrazine-PEG12-DBCO 95%
Methyltetrazine-DBCO 95%
DBCO-mPEG
DBCO-mPEG 5KDa  
DBCO-mPEG 10KDa  
DBCO-mPEG 20KDa  
DBCO-PEG-MAL,二苯基环辛炔PEG马来酰亚胺,(Dibenzocyclooctyne)PEG